The study aimed at deceloping an innovative teaching method.Chemo-entrepreneurship (CEP) approach is a method is Chemistry teching which relates the theory with everyday objects.This method provides the knowledge as well as the skills of Chemistry in order to transform raw materials into valuable products.The focus of the study was improvement of students achievement and the development of students life skills.The subjects of the study were 39 students from the Chemistry Education Departement of Universitas Negeri Semarang (UNNES).The data were abtained from the observation of the subjects which were finally analyzed descriptively.The result of the study showed that the CEP teching method was successfully implemented and the students gor better achievement.The study also revealed that the means of student s life skills were also improved.s achievement of learning was in creased.Students average life skills score was also improved.