Learning subject such as Natural Sciences (IPA) is not only leams about sciences concepts but also experiencing the real nature. This study aims to obtain information about students perceptions on the content of science laboratory practices The preparation of students in tutorials as well as expectations for practical implementation of IPA. Questionnaires were administered by mail and direct delivery. A total of 399 students from Medan Jakarta Samarinda Surabaya Bangka Belitung Mataram Palu which registered to the course at Universitas Terbuka(UT) in the first semester of 2009 has answered. Observation was carried out ar 4 locations in Sukabumi Depok Tangerang and Cisarua. The Results indicated that independent laboratory practices were done more compared to the formal tutorial practices. Perception of student towarda science laboratory activities of the of 4 scale (poor(1) fair (2) and good (4)) were respectively X 3.34 for student involvement in laboratory practices X 3.01 for the content material X 3.27 for the presence of tutors and expectations of students in consecutive tutorial activities was 0.71 for the availability of facilities and infrastructure 0.41 for to the availability of laboratory practice materials 0.31 for the competence of tutors and 0.33 for student involvement in laboratory practice activities.