One of approaches in comprehending al-Qur an is semantic or meaning approach. There are three ways to goin the meaning First is through microstucture that is to get the meaning of text through structural analysis of setence and phrase. Second stylistic that is the special stylistic of al-Qur an to be the tool to find the meaning of the text. Third semantic that is the choise of word or vocabulary used in al-Qur an has basic meaning and relational meaning. This paper is intended to observe the words the contain doa explicitly that is the verse of doa with the key word fi il madhi and amar . The research belongs to library research of qualitative approach. After analyzing the key word the conclusions are 1) The basic meaning of the key word in the verse of doa in al-Qur an has lexical meanig while the relational meaning is the meaning produced by the textual and contextual in this case the relational meaning of the verse of doa constitutes of synonim antonim and ambiguity. 2)In the verse of doa in al-Qur an the relational meaning is not always attached to the key word althought it is related to the other words it sometimes still has lexical meaning.